You can warp to a friend in San Fran but be warned if your character isn't up to scratch to complete the main mission that grants you access to San Fran, chances are your going to get destroyed. The enemies in San Fran are much harder than the mutants and raiders you've came up against thus far.
For me I'd say skipping to San Fran via a friend is like reading half a book then reading the last chapter.


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