That... could actually work! However, I don't really know what you could do with a show that has literally one permanent cast member while the rest of the crew is in stasis. I guess Nolan might have to make some new friends?
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The first two seasons were brilliant. A mystery was set up in the pilot episode, and it turned out to be merely the first piece in a puzzle that took 2 seasons to finish, at the end of which everything fell into place and made perfect sense. then in season 3, the writers clearly lost their shat. Irisa was ruined as a character and her history retconned in the worst possible way (and in a way that directly contradicted The Lost Ones), then she got herself together and we got one thoroughly awesome episode, then Nolan was ruined as a character (am I seriously expected to believe that a guy who had no problem being the Butcher of Yosemite will start PTSDing over the deaths of maybe 20 people under his command?), then we got the worst series finale since Battlestar Galactica. It was like the original writing team left and a bunch of people who knew absolutely nothing about the show were hired to replace them...